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Business Hours:
Monday - Friday:
8:30 am - 6:00 pm
8:30 am - 1:00 pm
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Crossroads Pharmacy accepts most all insurance companies as well as most debit and credit cards.
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Crossroads Pharmacy #2
401 Highway Street
Madison, NC 27025
Phone: 336-441-4041 (Option 2)
Fax: 336-916-0010

Also visit our store in Guilford County Crossroads Pharmacy #1
7605-B NC Hwy 68 N
Oak Ridge, NC 27310
Phone: 336-441-4041 (Option 1)

Serving Madison, NC
and surrounding areas
Since May, 2020
Serving Oak Ridge, NC
and surrounding areas
Since February, 2014
Due to the Covid-19 pandemic, we are currently only offering drive-thru or delivery at the Madison location and curb service or delivery at the Oak Ridge location in order to protect the safety of our customers and our staff. Please bear with us as we go through this.
Manage your prescriptions online with the RX Local app or at
Crossroads Pharmacy is a full service drug store that can meet all of your prescription and medical supply needs. In addition to filling your prescriptions, we offer a full line of over the counter medicines, vitamins and other medical supplies. We offer brand name products as well as the Good Neighbor Pharmacy Brand. If you need greeting cards for that special person or event, we can help you there too.

We now offer two locations to serve you. Our first location opened in Oak Ridge, NC in February, 2014. We are proud to have opened our second location in May, 2020 in Madison, NC.

Even though our first store opened in 2014, our pharmacists have experience that goes back much further. April Hinson Duggins, the owner started working in a pharmacy in 1997. She worked for K-Mart and Kerr Drug in Madison and The Drug Store in Stoneville. Tammy Wray, the full time pharmacist in Madison also worked at K-Mart in Madison as well as other locations.  With our combined experience you can trust Crossroads Pharmacy for all of your prescription needs.

All of our pharmacist are Immunization Certified for people that may need them.
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